Measuring Frailty in Patients Being Treated for Multiple Myeloma

Clinical Pearls Podcasts published on July 17, 2017
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R. Donald Harvey III, PharmD, FCCP, BCOP
Director, Phase I Program, Winship Cancer Institute
Assistant Professor, Hematology/Medical Oncology
Emory University School of Medicine
Atlanta, Georgia
Measuring Frailty in Patients Being Treated for Multiple Myeloma
  • Multiple methods for assessing the frailty of elderly patients with multiple myeloma
    • Frailty assessment important for identifying optimized multiple myeloma treatments and regimens to fit both the individual’s disease and degree
      of fitness
  • Measures of frailty to assess patients and their ability to tolerate treatment
    • Performance status
    • Age may not be an effective measure of frailty alone but is certainly a factor to be considered
    • The 2-minute walk test: the duration of distance that the patient may be able to walk over a 2-minute period
    • The time it takes for a patient to get up and out of the chair
  • Frailty measures more commonly used in the geriatric population but certainly have a role within our patients here with myeloma
    • Patients over the age of 80 may be at higher risk for increasing frailty
    • May be unable to tolerate more aggressive treatment, either in terms of dose or number of drugs prescribed
Last modified: June 16, 2017
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