Acute Lymphoblastic Leukemia: Nursing Notes on Asparaginase Hypersensitivity and Silent Inactivation

Based on the vital signs and reported physical exam findings, are you concerned that James is having an allergic reaction to his pegasparaginase?

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Based on James’ case, is there a way to help evaluate if he has a true allergy to pegasparaginase or if his reaction was infusion related?

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Based on the vital signs and reported physical exam findings, are you concerned that Amy has had an allergic reaction to her pegasparaginase?

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Based on Amy’s most recent asparaginase assay, would you want to alter any of her chemotherapy?

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Would you change the formulation of asparaginase that Amy is getting?

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